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December 4, 2025

Federal Health Agency Launches Comprehensive AI Strategy to Revolutionize Healthcare Operations

The U.S. Department of Health and Human Services just released a groundbreaking AI strategy that could transform how Americans receive healthcare. This first-of-its-kind initiative aims to integrate artificial intelligence across all federal health operations, from research to patient care delivery.

What's in the Five-Pillar AI Strategy?

HHS Acting Chief Artificial Intelligence Officer Clark Minor is leading an ambitious plan built on five core pillars:

  • Governance and Risk Management – Establishing trust through transparent AI oversight
  • Infrastructure Development – Building platforms designed for user needs across all HHS divisions
  • Workforce Development – Reducing administrative burdens while training staff on AI tools
  • Research Enhancement – Using AI to accelerate health research with "gold standard" scientific practices
  • Care Delivery Modernization – Improving patient outcomes through AI-powered healthcare services

A "OneHHS" Approach Breaking Down Silos

For the first time in the department's history, all major health agencies—including the CDC, CMS, FDA, and NIH—will collaborate on a unified AI infrastructure. This coordinated approach promises to streamline workflows and strengthen cybersecurity across the entire federal health system.

"AI has the potential to revolutionize health care and human services, and HHS is leading that paradigm shift," said Deputy Secretary Jim O'Neill. The strategy aligns with the Trump Administration's broader AI Action Plan and federal guidance from the Office of Management and Budget.

What This Means for Healthcare

Congressional leaders are already expressing support. Rep. Jay Obernolte, who chairs the Bipartisan House Task Force on Artificial Intelligence, praised HHS for taking a "thoughtful, outcomes-driven approach that prioritizes transparency" and protects Americans' health data.

The strategy focuses primarily on improving internal federal operations as a first step, with plans for future private sector partnerships to maximize AI's potential in healthcare delivery.

🔗 Read the full announcement on HHS.gov